We obtained a Proof of Concept (POC) grant from the European Research Council (ERC) to develop an innovative therapy targeting obesity-related liver cancer
The REPRO-PTP project targets tyrosine phosphatase proteins (PTP), a promising but still little therapeutically explored class of enzymes regulating cell signaling. The Signal Transduction and Metabolism Laboratory directed by Pr. Esteban Gurzov identified PTPRK, a receptor PTP that regulates glycolysis and lipogenesis, as a key player in obesity-related HCC. Based on cutting-edge research and proprietary inhibitors, REPRO-PTP aims to develop PTPRK inhibitors with unparalleled efficacy.
More information here.